Acetyl-Hexapeptide-8 (Argireline)
“Botox-like” topical peptide in cosmetic formulations targeting expression lines.
Overview
Cosmetic ingredient — subtle effects vs neuromodulator injections.
What it is
Acetylated hexapeptide SNAP-25 competitive mimic in cosmetic science.
Mechanism (high level)
Inhibits SNARE complex assembly in keratinocyte models — clinical depth varies by formula.
Quick facts
- Dosage
- Per serum concentration (often 5–10% in products)
- Route
- Topical
- Cycle
- 8+ weeks for cosmetic trials
- Storage
- Room temperature
Research indications
- Periorbital line cosmetic studies
Research protocols (education)
Education-first logging template
Use PepTok to track adherence and notes; any protocol must be directed by a qualified clinician.
Interactions
Often avoided with
- Layering with strong retinoids without tolerance
Often combined with
- Sunscreen daily
Peptides discussed online are not substitutes for diagnosis or prescriptions.
Side effects & safety
- Mild irritation — stop if dermatitis develops.
Regulatory notes
- Cosmetic ingredient; not a drug claim unless approved as such.
FAQ
Is this a prescription?
PepTok does not provide prescriptions; it is for logging and education.
Related in catalog
Track in app
Save favorites, compare protocols, and track over time
PepTok gives you structure: stacks, reminders, notes, and progress snapshots in one place.
Educational content only. This material is not medical advice. Verify legality, sourcing, and dosing with a qualified professional.